IL-22 anticorps

N° du produit ABIN7670665

Cet anticorps anti-IL-22 est un anticorps Souris Monoclonal détectant IL-22 dans ELISA (Detection). Adapté pour Humain.

Aperçu rapide pour IL-22 anticorps (ABIN7670665)

Antigène: IL-22 (IL22) (Interleukin 22 (IL22))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-22 est non-conjugé

Application: ELISA (Detection)

Clone: 4E6

Détail du produit anti-IL-22 anticorps

Fonction: IL-22 Monoclonal Antibody(Detector)

Purification: Protein A/G Purification

Immunogène: Recombinant Human IL-22 protein expressed by Mammalian

Isotype: IgG1

Information d'application

Indications d'application: ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur IL-22

Antigène: IL-22 (IL22) (Interleukin 22 (IL22))

Autre désignation: IL-22

Sujet: Cytokine Zcyto18,IL-10-reLated T-ceLL-derived inducibLe factor,IL22,IL-22,IL-D110,IL-TIF,ILTIFIL-10-reLated T-ceLL-derived-inducibLe factor,IL-TIFMGC79382,interLeukin 22,interLeukin-22,MGC79384,TIFa,TIFIL-23,zcyto18,Interleukin-22 (Il-22),also known as Il-10-related T cell-derived inducible factor (Il-TIF) was initially identified as a gene induced by Il-9 in mouse T cells and mast cells. Mouse Il-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79 % and 22 % aa sequence identity with human Il-22 and Il-10,respectively. The mouse Il-22 gene is localized to chromosome 10. Although it exists as a single copy gene in many mouse strains,the Il-22 gene is duplicated in some mouse strains including C57B1/6,FVB and 129. The two mouse genes designated Il-TIF alpha and Il-TIF beta,share greater than 98 % sequence homology in their coding region. Il-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. Il-22 is produced by normal mouse T cells upon Con A activation. Mouse Il-22 expression is also induced in various organs upon lipopolysaccharide injection,suggesting that Il-22 may be involved in inflammatory responses. The functional Il-22 receptor complex consists of two receptor subunits,Il-22 R (previously an orphan receptor named CRF2-9) and Il-10 R beta (previously known as CRF2-4),belonging to the class II cytokine receptor family.

UniProt: Q9GZX6